QUESTION 4 [TOTAL MARKS: 100] Q 4(a) [60 Marks] List three different functions that occur at heme active sites in metalloproteins. For each metalloprotein, outline the reaction occurring and describe how the active site is optimised for this function. Q 4(b) Enterobactin (below) is a bacterial siderophore. [40 Marks] OH . OH HN =O ΝΗ OH ОН OH OH i. ii. iii. Describe the function of siderophores and the mechanism by which they are utilised. How is enterobactin optimised for this function? Why do larger organisms require additional mechanisms to achieve the same function? Explain why some siderophores are useful in treating bacterial infections. iv. [End of Question 4]